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A full-time postdoctoral position is available in the Paw Laboratory, Division of Hematology, Brigham & Women’s Hospital, Harvard Medical School, in Boston, Massachusetts.  The general focus of our group centers on the developmental biology of hematopoiesis (blood).  Current projects include genetic screens to study red cell development and genetic mapping for candidate and positional cloning.  Functional studies of cloned genes are studied in zebrafish embryos and complementary model systems, such as mouse (cultured cells and transgenic mice) and yeast.

Our laboratory is strategically located in the Harvard Medical Area with ample opportunities to interact with other zebrafish labs and labs with interests in blood development.  Our zebrafish facility is situated in a ~2000-sq ft space with 1,200 community tanks with a full-time facility manager and ancillary support.

Representative publications:

  1. Shaw GC, et al., 2006 Nature 440:96-100.
  2. Chen W, et al. 2009 Proc. Natl. Acad. Sci. USA  106:16263-16268.
  3. Amigo JD, et al. 2009 Blood 114:4654-4663.
  4. Schultz IJ, et al. 2010 J. Biol. Chem. 285:26753-26759.
  5. Amigo JD, et al. 2011 Mol. Cell. Biol. 31:1344-1356.
  6. Shah DI, et al. 2012 Nature 491:608-612.
  7. Chen C, et al. 2013 Cell Metabolism 17:343-352.
  8. Hildick-Smith GJ, et al. 2013 Am. J. Hum. Genet. 93:906-914.
  9. Chung J, et al. 2014 J. Biol. Chem. 289:7835-7843.
  10. Yien YY, et al. 2014 J. Clin. Invest. 124:4294-4304.
  11. Chung J, et al. 2015 Sci. Signal. 8:ra35.
  12. Grillo A, et al. 2017 Science 356:608-616.
  13. Chung J, et al. 2017 eLife 6:e24767.  (doi: 10.7554/eLife.24767).
  14. Yien YY, et al. 2017 Proc. Natl. Acad. Sci. USA 114:E8045-E8052.

Candidates with strong background in molecular biology, developmental biology, genetics, or biochemistry are encouraged to apply.  Experience in zebrafish genetics and developmental biology is desirable, but not a requirement.  Training grant funding is available for candidates with U.S. citizenship or permanent residency. Interested candidates should send enquiries, curriculum vitae containing information about education, experience and publications, and a list of three individuals that can serve as references by E-mail to:

Barry Paw, M.D., Ph.D.
Division, Hematology BWH
Division, Hematology-Oncology BCH
Harvard Medical School

Tel: 617-525-4971
FAX: 617-525-0040

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